Metronidazole Injection USP is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis Metronidazole tablets are contraindicated during the first trimester of pregnancy see PRECAUTIONS.


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Contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives and during the first trimester of pregnancy.

What are contraindications for metronidazole. Metronidazole has been proved to be efficacious in treating. Metronidazole is a commonly used antibiotic belonging to the nitroimidazole class of antibiotics. Use of oral metronidazole is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently.

Metronidazole has important interactions with alcohol disulfiram and warfarin and there are contraindications to its use. 45 Metronidazole has been used as an antibiotic for several decades 15 with added antiparasitic properties that set it apart from. Patients should also avoid consuming alcohol or products containing propylene glycol while taking metronidazole and within three days of therapy completion.

Known hypersensitivity to metronidazole. Hypersensitivity to metronidazole or other nitroimidazoles although cautious desensitization has been applied Pregnancy 1st trimester controversial Use of disulfiram within past 2 weeks. Use with caution and reduce dose in severe hepatic impairment.

Abdominal cramps nausea vomiting headaches and flushing may occur if alcoholic beverages or products containing propylene glycol are consumed during or following metronidazole therapy see CONTRAINDICATIONS. Caution in preterm infants especially extreme immaturity. Terms in this set classification.

Metronidazole Flagyl Pharmacology antibiotic antiviral. Use of alcohol during therapy or within 3 days of discontinuing therapy. Metronidazole should not be given to patients who have taken disulfiram within the last two weeks see CONTRAINDICATIONS.

Psychotic Reaction with Disulfiram. Acute ulcerative gingivitis pericoronitis certain periapical infections some cases of osteomyelitis and infected socket. Metronidazole enhances the activity of warfarin and if metronidazole is to be given to patients receiving this or other anticoagulants the dosages of the latter should be recalibrated.

Dronabinol oral solution Syndros contains 50 ww dehydrated alcohol 55 ww propylene glycol which can produce disulfiramlike reactions if coadministered with metronidazole. Alcohol use during and for at least 3 days after use concomitant use within last 2 weeks of disulfiram vag gel hypersensitivity to metronidazole pregnancy. Flagyl is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives.

Infants with biliary tract obstruction. Caution in infants with jaundice liver dysfunction and biliary tract disease. With proper adherence to the instructions for the drug and careful adherence to the dosage the risk of side effects is small.

Contraindications and precautions. Warfarin and other Oral Anticoagulants. Alcoholic Beverages Abdominal cramps nausea vomiting headaches and flushing may occur if alcoholic beverages or products containing propylene glycol are consumed during or following metronidazole therapy see.

Metronidazole is contraindicated in neurological disease blood dyscrasias first trimester of pregnancy though no teratogenic effect has yet been demonstrated its mutagenic potential warrants caution and chronic alcoholism. Psychotic Reaction with Disulfiram. 14 It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis and amebiasis which are parasitic infections.

Nausea headache candida infection of genital region vaginal discharge and irritation. Meningitis not due to an infection low levels of a type of white blood cell called neutrophils alcoholism alcohol intoxication a low seizure threshold a painful condition that affects the nerves in the legs and arms called peripheral neuropathy prolonged QT interval on. Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol including abdominal cramps nausea vomiting headaches and flushing.

Effects of Drug Abuse. Rectal bleeding vomiting appendicitis and abdominal pain. Metronidazole increases toxicity of dronabinol by aldehyde dehydrogenase inhibition.

Can you take metronidazole for strep throat. Metronidazole by the rectal route is an effective alternative to the intravenous route when oral administration is not possible. Active CNS disease blood dyscrasias First trimester pregnancy breast feeding mothers.

Indications side effects contraindications and other prescribing information for Metronidazole on MIMS. The main side effects that can occur when taking Metronidazole are a sharp decrease in appetite loose stools nausea and allergic reactions. Discontinue consumption of alcohol or products containing propylene glycol during and for at least three days after therapy with metronidazole see PRECAUTIONS Drug Interactions.

Metronidazole is well absorbed orally and the intravenous route is normally reserved for severe infections. Metronidazole tablets are contraindicated in patients with a prior history of hypersensitivity to Metronidazole or other nitroimidazole derivatives. There is an increased haemorrhagic risk caused by decreased hepatic metabolism.

Some contraindications for laxatives are. In patients with trichomoniasis Flagyl is. Metronidazole is contraindicated in patients with documented hypersensitivity to the drug or its components and it should be avoided in first-trimester pregnancy.


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